Exam text content

 

Exam ELT-61226 Biomedical engineering: Biomaterials 16.10.2015

Examiner: Timo Allinniemi

Dictionaries are NOT allowed. No calculators.

Guestion 1.

a. Whatdo following terms mean? Explain shortly. (1 p each)

4

O (60 LIK TO

Biomaterial
Hydrolysis
Osteoinduction
Bioabsorbable
Biocompatibility
Implant

b. Based on your knowledge from this course, which kind of material(s) would you
use for the development of artificial skin? Which properties are important in the
material for this particular application? (4 p)

Ouestion 2.

a. Which are the main differences between synthetic bioabsorbable polymers and

natural bioabsorbable polymers? Give an example of a material for both of the
groups. (4 p)

b. Which are the main degradation mechanisms for these polymer groups? (2 p)

Ouestion 3.

a. Explain shortly the disadvantages that metals have as implantable biomaterials.
(5 p)
 

 

b. Explain the following graph after 10 years implantation. What has happened and
why? What's the role of the oxide layer? (4 p)

    

 

 
   
 
   
  

TIME
— FIBROUS
TISSUE INTEGRATION — CAPSULE -
»w FORMATIO
10 years

s —010—0"
Inm10nm 14m

Ouestion 4.

a. Living tissue can react in three ways when a foreign material is implanted in it.
Explain shortly these three ways. Give also one material example for each case

that causes that particular kind of reaction in the tissue. (3 Pp)

b. What happens in the tissue after implantation? Explain shortly. (4 p)

Ouestion 5.

One of the particularity of ceramics lies in the fact that they can be either nearly
inert, bioresorbable or even bioactive. If the application reguires bioactivity, what
would be the ceramic you would like to use? Describe also the process of

pioactivity. (4 p)