Exam text content

ELT-72106 Cellular Interactions - 20.05.2014

Exam text content

The text is generated with Optical Image Recognition from the original exam file and it can therefore contain erroneus or incomplete information. For example, mathematical symbols cannot be rendered correctly. The text is mainly used for generating search results.

Original exam

 

ELT 72106 Cellular Interactions
Exam on 20.5.2014

Jari Hyttinen

1. Explain briefly:

Local adhesion in cells
Micro electrode array (MEA)
Gap-junction in cells

. Patch Clamp measurement

aeop

2. Mechanisms of mechanosensing in cells
3 Kerro-esimerkki miten-voit mallintaa sydänsolun ionikanavia ja aktiopotentiaalia?

4. Describe an example how to make mathematical model of a single ion channel or
myocardial action potential?

5. a)A cell in 37*C temperature has the following ionic concentrations and membrane

 

 

 

 

permeabilities:
Intracellular Extracellular Relative
concentration(mM) |concentration (mM) |permeability
K= = 5 1
Na 15 140 0.05
5
ET 5 110 0.45

 

 

 

 

 

 

Calculate the resting membrane potential of the cell using the Goldman-Hodgkin-Katz
eguation.

Constants:
J

J = äs 19)
R=8.3145 K mol , F=96485 779 , ks=1.3807*10% K ,e=1.602*109%

 

b) Describe the meaning and purpose of the Goldman-Hodgkin-Katz eguation — compare it to
Nernst eguation?

We use cookies

This website uses cookies, including third-party cookies, only for necessary purposes such as saving settings on the user's device, keeping track of user sessions and for providing the services included on the website. This website also collects other data, such as the IP address of the user and the type of web browser used. This information is collected to ensure the operation and security of the website. The collected information can also be used by third parties to enable the ordinary operation of the website.

FI / EN